1 HN user recommended this lecture1 month2014–2025score 1.5
Years with an HN recommendation, 2007–2026
HN points to it as an accessible, interesting talk on molecular dynamics and simulation-based drug discovery.
David Shaw of D. E. Shaw Research presents Anton, a special-purpose machine that speeds up biomolecular simulations about a hundred-fold. The lecture covers molecular dynamics and how simulation helps understand how drugs bind.
“There is brilliant video by the hedge fund manager DE Shaw about molecular dynamics simulation. Its very accessible and I found it very interesting” (HN, 2025)
There is brilliant video by the hedge fund manager DE Shaw about molecular dynamics simulation. Its very accessible and I found it very interesting — [this video]
Accessible, interesting talk by DE Shaw on molecular dynamics simulation.
I'm not giving you what you want, but here's a visual example of using a computational microscope to understand how drug actually works and finds its binding site: [this video] If you can't see a difference between that and say, X-Ray crystallography then well..
Visual example of a computational microscope showing how a drug finds its binding site.
> What do you mean by fundamental AI research? Coming up with new/original models that solve the same exact problems that people are trying to solve with neural networks (computer vision, language translation, image generation etc) hopefully that are better performing & cheaper computationally. > What kind of computational model? I think answering that question would be what the researcher in this field is trying todo. I think a place to start would be exploring abandoned AI strategies like Genetics Algorithms & Markov Logic >What are some practical applications of complex systems? - Modeling Financial Markets [1] - Drug discovery via Molecular Dynamics Simulations [2] - Urban Planning [3] - Modeling Epidemics [4] - Cosmology - Computer Graphics - Much more .... [1]: [link] [2]: [this video] [3]: [link] [4]: [link] If interested, subscribe to these podcasts. 1: Simplifying Complexity: [link] 2: Complexity: [link]
Cited as an example of drug discovery via molecular dynamics simulation.
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